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Can Magnesium Help With Insulin Resistance?

Written and medically reviewed by Kelsey Stalvey, PharmD
Posted on August 5, 2024

Imagine a simple mineral that could help manage blood sugar levels, potentially ward off diabetes complications, and improve overall health. Sounds too good to be true? Enter magnesium, an essential nutrient that is garnering attention for its potential role in combating insulin resistance. Let’s dive into what magnesium is, how it affects insulin sensitivity, and whether it might be a useful supplement for those managing diabetes.

What Is Magnesium?

Magnesium is a mineral found abundantly in the earth, sea, plants, animals, and humans. It’s crucial for more than 300 biochemical reactions in the body, including muscle and nerve function, blood sugar control, and blood pressure regulation. Despite its importance, many people don’t get enough magnesium in their diets, which can lead to various health issues.

Sources of magnesium in the diet include leafy green vegetables, nuts, seeds, whole grains, and legumes. For example, a handful of almonds or a serving of spinach can significantly contribute to your daily magnesium intake. Magnesium is also available as a supplement, making it easier for people with dietary restrictions to get enough.

How Does Magnesium Affect Insulin Sensitivity?

Insulin is a hormone that helps control the amount of sugar in your blood. It works by allowing sugar to enter your cells, where it can be used for energy. Insulin resistance occurs when cells don’t respond well to insulin, leading to higher blood sugar levels and an increased risk of type 2 diabetes. Magnesium plays a critical role in glucose metabolism (how your body processes sugar) and insulin action. Low magnesium levels are associated with reduced insulin secretion and insulin sensitivity, whereas higher magnesium intake has been linked to improved insulin sensitivity and lower fasting blood glucose levels.

One study published in the journal Diabetes Care found that individuals with higher magnesium intake had a 15 percent to 23 percent lower risk of developing type 2 diabetes compared to those with the lowest intake.

Should People With Type 1 Diabetes Supplement With Magnesium if They’re Insulin Resistant?

Type 1 diabetes is an autoimmune condition where the body attacks and destroys insulin-producing cells in the pancreas. Although type 1 diabetes is not caused by insulin resistance, individuals with this condition can still develop insulin resistance, known as double diabetes. For these people, magnesium supplementation may offer some benefits. Per the journal Medicine, research in children indicates that magnesium can improve insulin sensitivity and metabolic control in those with type 1 diabetes. However, it’s important to be careful with supplements. Always talk to a health care professional to find the right dosage and check your magnesium levels. Your doctor can provide personalized advice based on your health needs and conditions.

Should People With Type 1 Diabetes Take Supplements?

Even if insulin resistance isn’t a concern, magnesium supplementation can still be helpful for those with type 1 diabetes in addition to standard treatment. People with diabetes often have low magnesium levels because they lose more of the mineral through urine. Supplementing with magnesium can help manage blood sugar levels, reduce the risk of cardiovascular disease, and improve overall health.

For example, one review in the journal Open Heart found that magnesium supplementation helped reduce heart arrhythmias (irregular heartbeats) in people with diabetes. Because cardiovascular disease is a major complication of diabetes, keeping your magnesium levels up can greatly benefit your heart health.

What Are the Possible Risks of Magnesium Supplements?

While magnesium supplements can be beneficial, they are not without risks. High doses of magnesium from supplements can cause adverse effects such as diarrhea, nausea, and abdominal cramping. In severe cases, excessive magnesium intake can lead to magnesium toxicity, which can cause symptoms like muscle weakness, difficulty breathing, and irregular heartbeat.

Additionally, certain medical conditions and medications can interact with magnesium supplements. For instance, people with kidney disease may have trouble eliminating excess magnesium, leading to dangerous levels in the body. Similarly, magnesium can interact with medications such as antibiotics, diuretics, bisphosphonates, and proton pump inhibitors, affecting how well they work or causing harmful side effects.

To minimize risks, it’s crucial to use magnesium supplements under the guidance of a health care provider. They can help you choose the right form of magnesium (such as magnesium citrate, magnesium oxide, or magnesium glycinate) and the appropriate dosage to suit your needs.

Understanding Different Magnesium Formulations

Magnesium supplements come in different forms, and each form is absorbed by your body at different rates. This means some kinds of magnesium are more easily used by your body than others. According to a review of several studies on magnesium supplements, organic forms of magnesium, such as magnesium citrate and magnesium glycinate, allow more magnesium to have an active effect on the body than inorganic forms like magnesium oxide. This means that the body can absorb and use organic types of magnesium more effectively.

For example, magnesium citrate absorbs well in the body, making it a popular choice for those needing to boost their magnesium levels quickly. Magnesium glycinate is another excellent option, especially for individuals with sensitive stomachs, as it tends to be gentler on the digestive system. On the other hand, magnesium oxide, although it contains a higher amount of magnesium, doesn’t dissolve as well into the body, meaning it may not raise magnesium levels as easily.

Talk to Your Doctor

Before adding any supplement to your routine, check with your doctor. Your health care provider can help you determine if you need a magnesium supplement and what dosage would be appropriate. They can also monitor your magnesium levels and adjust your treatment plan as needed to ensure your safety and well-being.

Discussing your supplement regimen with your doctor is particularly important if you have any underlying health conditions or are taking medications that could interact with magnesium. By doing so, you can prevent potential complications and ensure that any supplements you take are beneficial for your health.

Is Magnesium Right for You?

Magnesium is an essential mineral that plays a vital role in many bodily functions, including insulin sensitivity. Incorporating magnesium-rich foods into your diet can help you meet your magnesium needs naturally and support your health in the long term. For people with insulin resistance, including those with type 1 diabetes, magnesium supplementation may offer some benefits.

Although magnesium can play a helpful role in managing insulin resistance and overall health, it’s essential to approach supplementation with care and professional guidance. Doing so ensures that you reap the benefits while minimizing potential risks, ultimately supporting your journey toward better health and well-being.

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Have you talked about magnesium with the doctor managing your type 1 diabetes? Share your experience in the comments below, or start a conversation by posting on your Activities page.

Posted on August 5, 2024
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Kelsey Stalvey, PharmD received her Doctor of Pharmacy from Pacific University School of Pharmacy in Portland, Oregon, and went on to complete a one-year postgraduate residency at Sarasota Memorial Hospital in Sarasota, Florida. Learn more about her here.

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